The Reversade Laboratory

human embryology & genetics

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Our laboratory studies the development of the human embryo.
To understand how normal embryogenesis takes place
we investigate genetic conditions that trigger birth defects or
unusual phenotypes such as twinning.

Starting from rare human pedigrees we use animal models,
tools from genetics, molecular biology and biochemistry to address
how a single cell develops into a complete human being or
sometimes two.

Our first objective is to understand how human identical twins
are formed. Known as monozygotic (MZ), identical twins arise
when two babies develop from one embryo. Truly monoclonal
MZ twins are reproductive clones and yet sovereign human beings.

This extraordinary mode of development is obligate in nine-banded
armadillos which have MZ quadruplets each and every time they breed.