Our research aims at understanding the principals governing normal embryonic

development in hopes of determining the cause of human birth defects.

We use various model organisms as well as rare human pedigrees and combine

tools from genetics, biochemistry, and molecular biology to answer these questions.

We have a particular focus on elucidating the genetic basis of monozygotic twinning

in humans, a form of natural reproductive cloning which allows the making of two

perfect babies out of a single fertilized egg.