IRX5 & Hamamy Syndrome
PYCR1 & Wrinkly Skin Syndrome
CHSY1 & Brachydactyly
Our research aims at understanding the principals governing normal embryonic
development in hopes of determining the cause of human birth defects.
We begin with rare or orphan genetic diseases, and use various model organisms,
tools from genetics, biochemistry and molecular biology to better understand these
diseases towards improved diagnosis and therapeutics.
We are particular focused on elucidating the genetic basis of monozygotic twinning
in humans, a form of natural reproductive cloning which allows the making of two
perfect babies out of a single fertilized egg.